The 495/MetroWest Corridor Region includes 32 cities and towns located along Route 495 from Route 2 in the north to Route 1 in the south. Route 495 is the major north-south thoroughfare, while east-west travel in the region is convenient via several arteries including the Massachusetts Turnpike and Route 9.

The communities of the region house a population of about 537,000 persons and a labor force of about 295,000 workers. Most of the jobs in the area are found in Trade, Transportation and Utilities; Professional and Business Services and Manufacturing.